Patent · US Active

Background-suppressed myelin water imaging

US9851425B2 · kind B2 · utility

3Cited by

2References

12Claims

0Family size

Assignee

The Trustees of the University of Pennsylvania · US

Inventors

Jongho Lee · Suwon-si, KR
Sehong Oh · Philadelphia, US

Key dates

Filing date	Nov 26, 2013
Grant date	Dec 26, 2017
Priority date	—
Expiry date	Dec 4, 2034

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/30016
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A technique and associated imaging system is provided that selectively acquires the myelin water signal by utilizing a multiple inversion RF pulses to suppress a range of long T1 components including those from axonal and extracellular water. This leaves the myelin water, which has been suggested to have short T1, as the primary source of the image. After long T1 suppression, the resulting image is dominated by short T2 in the range of the myelin water (T2*<20 ms at 3 T). This result confirms that the short T1 component has short T2* and, therefore, the resulting image is a myelin water image.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.