Polyglutamate-amino acid conjugates and methods

US9855338B2 · kind B2 · utility

Assignee

• NITTO DENKO CORPORATION · JP

Inventors

• Lei Yu · Huangguan, CN
• Gang Zhao · Oceanside, US
• Sang Van · San Diego, US
• Sanjib Kumar Das · Morrisville, US
• Zhongling Feng · San Diego, US
• Xiaoli Fu · Vista, US
• Xinghe Wang · San Diego, US
• Yi Jin · Winnipeg, CA
• Fu-Tai A. Chen · Brea, US

Key dates

• Filing date: Nov 17, 2016
• Grant date: Jan 2, 2018
• Expiry date: Nov 17, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/64
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, biomolecule and imaging agent delivery applications.