Implantable material grafted with a cell antiproliferative and/or antibacterial film synthetized from a bifunctional molecule
US9855373B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 13, 2014 |
| Grant date | Jan 2, 2018 |
| Priority date | — |
| Expiry date | Jul 21, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/16
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to an implantable material having at least one external surface grafted with a film including carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on the external surface by radical reaction of a bifunctional adhesion primer of Formula (I) or by radical reaction of an adhesion primer and a bifunctional polymerizable monomer of Formula (II).The invention also relates to a process for directly synthesizing and grafting of a film according to the invention onto at least one external surface of an implantable material. The invention further relates to the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device. The invention also relates to compounds of Formula (I) and Formula (II).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.