Therapeutics targeting truncated adenomatous polyposis coli (APC) proteins
US9856233B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Sep 10, 2014 |
| Grant date | Jan 2, 2018 |
| Priority date | — |
| Expiry date | Sep 10, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The described invention provides small molecule anti-cancer compounds that selectively target and inhibit measurable biological activity of truncated APC proteins, an immortalized Human Colonic Epithelial Cell (HCEC) model, and pharmaceutical compositions comprising at least one of the small molecule anti-cancer compounds and a pharmaceutically acceptable carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.