Tripeptide epoxyketone compound constructed by heterocycle and preparation method and use thereof

US9856288B2 · kind B2 · utility

Assignees

• ZHEJIANG UNIVERSITY · CN
• SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

• Yongzhou Hu · Zhejiang, CN
• Jia-He Li · Cockeysville, US
• Tao Liu · Shanghai, CN
• Jiankang ZHANG · Zhejiang, CN
• Yubo Zhou · Shanghai, CN
• Bo Yang · Zhejiang, CN
• Qiaojun HE · Hangzhou City, CN
• Lei Xu · Ottawa, CA
• Xiaobei Hu · Shanghai, CN

Key dates

• Filing date: Mar 11, 2015
• Grant date: Jan 2, 2018
• Expiry date: Mar 11, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are a tripeptide epoxyketone compound, a preparation method thereof, and a use thereof in the preparation of anti-tumor drugs.