Spider silk fusion protein structures incorporating immunoglobulin fragments as affinity ligands
US9856308B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 2, 2013 |
| Grant date | Jan 2, 2018 |
| Priority date | — |
| Expiry date | Feb 21, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A recombinant fusion protein comprising the moieties Band CT, and optionally REP, wherein B is comprising at least one immunoglobulin fragment, which provides the capacity of selective interaction with an organic target; CT is a moiety of from 70 to 120 amino acid residues and is derived from the C-terminal fragment of a spider silk protein; and REP is a moiety of from 70 to 300 amino acid residues and is derived from the repetitive fragment of a spider silk protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.