Formulations for treating amyloidosis
US9856475B2 · kind B2 · utility
4Cited by
27References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 23, 2015 |
| Grant date | Jan 2, 2018 |
| Priority date | — |
| Expiry date | Jul 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides pharmaceutical compositions containing a UNA oligomer targeted to TTR and a pharmaceutically acceptable carrier. The compositions can be used in methods for treating or preventing TTR-related amyloidosis in a primate. The compositions, upon administering a single dose to the primate, can reduce TTR protein in the primate for a period of days to weeks.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.