GPR142 agonist compounds

US9861613B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Zhi Long Hu · Zhongshan, CN
• Lian Zhu Liu · Shanghai, CN
• Tianwei Ma · Carmel, US
• Mi Zeng · Shanghai, CN
• Jingye Zhou · Shanghai, CN

Key dates

• Filing date: Jan 22, 2015
• Grant date: Jan 9, 2018
• Expiry date: Jan 22, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2121/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides compounds of the Formula (Ia) wherein R is selected from the group consisting of CH3, CH(CH3)2, CH2CN, CH2CHF2, CH2CF3, (A), (B), (C), (D), (E), (F), CH2CH2OCH3, and CH2C(O)OCH(CH3)2; R1 is selected from the group consisting of CF3, OCF3, and Cl; R2 is selected from the group consisting of H and F; or a pharmaceutically acceptable salt thereof.