Macrocycles as kinase inhibitors

US9861635B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Guenter Hoelzemann · Seeheim-Jugenheim, DE
• Dieter Dorsch · Ober-Ramstadt, DE
• Ansgar Wegener · Heusenstamm, DE
• Oliver Poeschke · Wiesbaden, DE
• Michael Busch · Darmstadt, DE

Key dates

• Filing date: Apr 9, 2014
• Grant date: Jan 9, 2018
• Expiry date: Apr 27, 2034

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula Iin which X, Y, Q1, M, Q2 and B have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.