Method for in-vitro preparation of double-layered virus-like particles of rotavirus
US9862933B2 · kind B2 · utility
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Key dates
| Filing date | Jun 24, 2013 |
| Grant date | Jan 9, 2018 |
| Priority date | — |
| Expiry date | Jul 10, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2720/12352
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a method for preparing double-layered virus-like particles of rotavirus in vitro. The method comprises the following steps: purifying rotavirus VP6 proteins from a lysis supernatant, and in vitro assembling double-layered virus-like particles consisting of VP2 proteins and VP6 proteins, wherein the proteins and the virus-like particles can be used for preventing or reducing the clinical symptoms caused by rotavirus infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.