Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases
US9862982B2 · kind B2 · utility
9Cited by
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18Claims
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Key dates
| Filing date | May 25, 2016 |
| Grant date | Jan 9, 2018 |
| Priority date | — |
| Expiry date | May 25, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid sequence of a Halorhabdus utahensis cellulase, such as Hu-CBH1, wherein said amino acid sequence has a halophilic thermostable and/or thermophilic cellobiohydrolase (CBH) activity. In some embodiments, the polypeptide has a CBH activity that is resistant to up to about 20% of ionic liquids. The present invention also provides for compositions comprising and methods using the isolated or recombinant polypeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.