Method for scoring pathology images using spatial statistics of cells in tissues
US9865053B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2016 |
| Grant date | Jan 9, 2018 |
| Priority date | — |
| Expiry date | Jul 2, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The disclosure concerns a method for extracting geographic distribution statistics from patient tissue samples assayed with a tissue-based test for the purpose of scoring the patient tissue samples and guiding treatment based on the score(s). The method described herein utilizes digital image analysis of an image of one or more tissue sections to extract object-based (e.g., cells) features to generate a data array representing said tissue numerically in image analysis feature space. The numerical representation of the image of the tissue section in image analysis feature space is further processed using one or more algorithm processes to extract sophisticated geographical distribution features of one or more object type or sub-type in the tissue. Statistics describing the geographic distribution features are summarized to generate a patient-specific diagnostic score, and this score can be evaluated to guide patient treatment decisions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.