Patent · US Active

Cycloalkylamines as monoamine reuptake inhibitors

US9868718B2 · kind B2 · utility

0Cited by
41References
2Claims
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Assignee

Inventors

Key dates

Filing dateSep 30, 2014
Grant dateJan 16, 2018
Priority date
Expiry dateSep 30, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.