Modulators of protease activated receptors

US9868763B2 · kind B2 · utility

Assignee

• The University Of Queensland · AU

Inventors

• David Fairlie · Faulconbridge, AU
• Ligong Liu · Calle de la Era, AU
• Mei Kwan Yau · Brisbane, AU
• Jacky Yung Suen · Brisbane, AU
• Robert C. Reid · Calle de la Era, AU
• Rink-Jan Lohman · Brisbane, AU
• Abishek Venkatasubramanian Iyer · Brisbane, AU
• Junxian Lim · Brisbane, AU
• Lindsay Brown · Cambridge, GB

Key dates

• Filing date: Jul 27, 2012
• Grant date: Jan 16, 2018
• Expiry date: Jul 27, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K5/06078
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for therapies such as metabolic syndrome, obesity, type II diabetes, fibrosis and cardiovascular diseases, whether they are used alone or in combination with other treatment modalities.