Recombinant Der P 2 expressed in Pichia Pastoris as a “natural-like” allergen for immunotherapy and diagnostic purposes
US9868770B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | May 17, 2011 |
| Grant date | Jan 16, 2018 |
| Priority date | — |
| Expiry date | May 17, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P21/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention concerns a method for producing a recombinant Dermatophagoides pteronyssinus 2 protein (rDer p 2), comprising the steps of cultivating a Pichia pastoris yeast strain previously transformed with a rDer p 2 coding sequence, and isolating the rDer p 2 protein from said Pichia pastoris yeast strain. The invention also relates to compositions and kits comprising the rDer p 2 protein for therapeutic or diagnostic use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.