Compositions and methods for “resistance-proof” SiRNA therapeutics for influenza
US9868952B2 · kind B2 · utility
0Cited by
6References
22Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 7, 2013 |
| Grant date | Jan 16, 2018 |
| Priority date | — |
| Expiry date | Jul 7, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions and methods for development of resistance-proof siRNA therapeutics for prevention and treatment of influenza viral infections. The compositions include a pharmaceutical composition comprising siRNA molecules that target conserved regions of an influenza virus gene and a pharmaceutically acceptable polymeric carrier. In one embodiment, the polymeric carrier condenses the molecules to form a nanoparticle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.