Anti-staphylococcal antibodies

US9873733B2 · kind B2 · utility

Assignees

• MORPHOSYS AG · DE
• Universitatsklinikum Tubingen · DE

Inventors

• Christoph ERNST · Lörrach, DE
• Andreas Peschel · Wolfratshausen, DE
• Alexandra Kraus · Munich, DE
• Michael Tesar · Heidelberg, DE

Key dates

• Filing date: Dec 20, 2013
• Grant date: Jan 23, 2018
• Expiry date: Jan 25, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/76
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This disclosure generally relates to antibodies or fragments thereof which interact with the bacterial protein MprF. The disclosure further discloses antibodies, which bind to specific extracellular motifs of MprF. The disclosure further relates to therapeutics comprising MprF-specific antibodies and methods of treatment using MprF-specific antibodies or fragments thereof.