5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group

US9877954B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Ulrich Lücking · Berlin, DE
• Niels Böhnke · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Gerhard Siemeister · Berlin, DE
• Ulf Bömer · Glienicke, DE
• Dirk Kosemund · Berlin, DE
• Rolf Bohlmann · Berlin, DE
• Ludwig Zorn · Berlin, DE

Key dates

• Filing date: Apr 3, 2017
• Grant date: Jan 30, 2018
• Expiry date: Apr 3, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).