GDF-8 inhibitors
US9878992B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 13, 2017 |
| Grant date | Jan 30, 2018 |
| Priority date | — |
| Expiry date | Jul 13, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65038
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are GCF-8 inhibitors of the formula (I),and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R5, R6, X and Z are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for inhibiting GDF-8 in a cell and methods for treating a patient suffering from a disease or disorder, wherein the patient would therapeutically benefit from an increase in mass or strength of muscle tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.