Patent · US Active

Synthetic peptide for repressing transcription and/or gene expression from a binding site of interest

US9879051B2 · kind B2 · utility

0Cited by

3References

16Claims

0Family size

Assignee

The Research Foundation for The State University of New York · US

Inventors

Christopher T. Nomura · Syracuse, US
Benjamin R. Lundgren · Syracuse, US

Key dates

Filing date	Jun 7, 2016
Grant date	Jan 30, 2018
Priority date	—
Expiry date	Jun 7, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6897
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A synthetic peptide includes an amino acid sequence that: has 70-75%, 75-80%, 80-85%, 85-90%, 90-95% or 95-100% homology with an RpoN box of Region III of an RpoN protein; and binds specifically to a −24, −12, or −24/−12 site(s) of an RpoN promoter. The synthetic peptide is effective for repressing transcription and/or gene expression from a binding site of interest, and the binding site of interest is an RpoN binding site or a cryptic promoter upstream of an RpoN binding site.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.