Method and array for identifying histone-code-related analytes
US9879300B2 · kind B2 · utility
1Cited by
1References
33Claims
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Key dates
| Filing date | Jun 11, 2014 |
| Grant date | Jan 30, 2018 |
| Priority date | — |
| Expiry date | Feb 21, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2440/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed embodiments concern an array for use in identifying or identifying and quantifying analytes in a sample using a macrocyclic sensor comprising a macrocyclic compound and a detectable moiety. The disclosed array may be used to discriminate among various analytes based on different features, such as post-translational modifications, isomeric post-translational modifications, and the peptide sequence around post-translational modifications. Also disclosed is a method for identifying analytes comprising a post-translational modification, as well as an enzymatic assay using the disclosed macrocyclic sensor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.