Inhibitors of 17Beta-hydroxysteroid dehydrogenases type 1 and type 2

US9884839B2 · kind B2 · utility

Assignee

• ElexoPharm GmbH · DE

Inventors

• Rolf Hartmann · Saarburg, DE
• Martin Frotscher · Pocking, DE
• Ahmed Saad Abdelsamie Ahmed · Shubra al Khayma, EG
• Emmanuel Bey · Enzklösterle, DE
• Chris J. van Koppen · Kleve, DE
• Sandrine Oberwinkler-Marchais · Marburg, DE
• Carsten Börger · Riegelsberg, DE
• Lorenz Siebenbürger · Riegelsberg, DE
• Victor Hernández Olmos · Riegelsberg, DE

Key dates

• Filing date: Jan 5, 2015
• Grant date: Feb 6, 2018
• Expiry date: Jan 5, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided herein are non-steroidal 17beta-hydroxysteroid dehydrogenase type 1 and type 2 (17β-HSD1 and 17β-HSD2) inhibitors, their production and use, especially for the treatment and for prophylaxis of hormone-related diseases.