Patent · US Active

Fused pyrroledicarboxamides and their use as pharmaceuticals

US9884860B2 · kind B2 · utility

1Cited by

0References

15Claims

0Family size

Assignee

Sanofi · FR

Inventors

Laurent Bialy · Frankfurt am Main, DE
Katrin Lorenz · Frankfurt am Main, DE
Klaus Wirth · Frankfurt am Main, DE
Klaus Steinmeyer · Frankfurt am Main, DE
Gerhard Hessler · Hofheim, DE

Key dates

Filing date	Feb 11, 2016
Grant date	Feb 6, 2018
Priority date	—
Expiry date	Feb 11, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D513/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates in fused pyrroledicarboxamides of the formula (I), in which R1 to R9, X, m and n are as defined in claims. The compounds of the formula (I) are inhibitors of the acid-sensitive potassium channel TASK-1 and suitable for the treatment of TASK-1 channel-mediated diseases such as arrhythmias, in particular atrial arrhythmias like atrial fibrillation or atrial flutter, and respiratory disorders, in particular sleep-related respiratory disorders like sleep apnea, for example.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.