Patent · US Active

Anti-NGF compositions and use thereof

US9884909B2 · kind B2 · utility

1Cited by
131References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 15, 2013
Grant dateFeb 6, 2018
Priority date
Expiry dateMar 15, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/94
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.