Patent · US Active

Molecular affinity clamp technology and uses thereof

US9885050B2 · kind B2 · utility

3Cited by
9References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 10, 2008
Grant dateFeb 6, 2018
Priority date—
Expiry dateMar 8, 2031

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/71
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The invention provides a molecular affinity clamp. The architecture of the affinity clamp is modular with two biorecognition modules, each capable of binding a target motif. The first biorecognition module has a recognition domain that possesses inherent or natural specificity for the target motif. The second biorecognition module also has a recognition domain that binds the motif. The two biorecognition modules are tethered together either directly, e.g., via a peptide bond between the two modules, or indirectly, e.g., via a linker moiety or linker.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.