Patent · US Active

Embodiments of a probe and method for targeting nucleic acids

US9885082B2 · kind B2 · utility

12Cited by
18References
32Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 19, 2012
Grant dateFeb 6, 2018
Priority date—
Expiry dateMar 31, 2034

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/143333
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed embodiments concern a probe comprising one or more pairs of monomers capable of targeting a nucleic acid target. The pair of monomers may be arranged in a manner that promotes thermoinstability of the probe complex, thus producing a probe capable of locating and/or detecting a target. The probe also may comprise one or more natural or non-natural nucleotides capable of Watson-Crick base pairing with an isosequential nucleic acid target. Particular disclosed embodiments concern a method of using the disclosed probe to target nucleic acids. In particular disclosed embodiments, the probe may be incubated with a target nucleic acid and then be detected.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.