Materials and methods for detection of HPV nucleic acids
US9885092B2 · kind B2 · utility
1Cited by
96References
33Claims
0Family size
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Key dates
| Filing date | Feb 23, 2012 |
| Grant date | Feb 6, 2018 |
| Priority date | — |
| Expiry date | Nov 28, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6825
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are nucleic acids capable of hybridizing to HPV 16 and/or HPV 18 nucleic acids, in particular, mRNA encoding E2 and E6-7 gene products. Such nucleic acids are useful in methods of isolating RNA from a biological sample, methods and means for determining the presence of particular RNA splice-form variants in a biological sample, methods and means for determining the relative ratio of RNA ratios in a biological sample, methods and means for predicting the progression of precancerous cervical lesions, and methods and means for detecting disruption of genes or gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.