Methods for processing whole blood samples, and compositions for use in practicing the same
US9885699B2 · kind B2 · utility
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1References
18Claims
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Key dates
| Filing date | Jun 10, 2015 |
| Grant date | Feb 6, 2018 |
| Priority date | — |
| Expiry date | Oct 5, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/016
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for processing whole blood samples are provided. Aspects of the methods include depleting leukocytes from a whole blood sample to produce a leukocyte depleted sample, and then lysing red blood cells (RBCs) in the resultant leukocyte depleted sample to produce a leukocyte/RBC depleted sample. Also provided are compositions and kits for practicing embodiments of the invention. The methods and compositions find use in a variety of different applications, including the detection of circulating tumor cells (CTCs).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.