Patent · US Active

Method for modulating a bacterial invasion switch

US9889185B2 · kind B2 · utility

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8Claims

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Assignee

RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK · US

Inventors

Haiping Cheng · New York, US
Shari Walcott · New York, US
Haiyang Lu · Jinan, CN
Li-Di Luo · Hsinchu, TW
Menghua Yang · New York, US
Zahra Salehi · New York, US

Key dates

Filing date	Sep 14, 2015
Grant date	Feb 13, 2018
Priority date	—
Expiry date	Sep 14, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N9/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The subject matter disclosed herein pertains to the modulation of a bacterial invasion switch and the subsequent use of the bacterium to vaccinate an organism. In one embodiment, the bacterial invasion switch is modulated by changing the proteolysis of ExoR protein. In another embodiment, a mutated bacterium produces a mutant ExoR protein that resists proteolysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.