Micro-fluidic devices for assaying biological activity
US9889445B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 22, 2014 |
| Grant date | Feb 13, 2018 |
| Priority date | — |
| Expiry date | Feb 12, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB03C2201/26
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Biological activity in holding pens in a micro-fluidic device can be assayed by placing in the holding pens capture objects that bind a particular material of interest produced by the biological activity. The biological material of interest that binds to each capture object can then be assessed, either in the micro-fluidic device or after exporting the capture object from the micro-fluidic device. The assessment can be utilized to characterize the biological activity in each holding pen. The biological activity can be production of the biological material of interest. Thus, the biological activity can correspond to or arise from one or more biological cells. Biological cells within a holding pen can be clonal cell colonies. The biological activity of each clonal cell colony can be assayed while maintaining the clonal status of each colony.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.