Urea derivatives useful as kinase inhibitors
US9890185B2 · kind B2 · utility
7Cited by
32References
18Claims
0Family size
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Key dates
| Filing date | Dec 19, 2014 |
| Grant date | Feb 13, 2018 |
| Priority date | — |
| Expiry date | Dec 19, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65586
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are provided compounds of formula I, wherein R1, R1A, R1C to R1E, Ra, Rb, X1, E and G have meanings given in the description, which compounds have antiinflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.