Patent · US Active

Staphylococcus aureus SpA5 mutant, composition comprising mutant and preparation method and use thereof

US9890199B2 · kind B2 · utility

0Cited by

0References

13Claims

0Family size

Assignees

Olymvax Biopharmaceuticals Inc. · CN
Third Military Medical University, PLA · CN

Inventors

Quanming Zou · Chongqing, CN
Hao Zeng · Chongqing, CN
Shaowen Fan · Chongqing, CN
Lu Lu · San Diego, US
Qiang Feng · Qingdao, CN
Jinyong Zhang · Chongqing, CN
Haiming Jing · Chongqing, CN
Yandong Dong · Chongqing, CN
Yi-Chia Wu · Taichung, TW
Changzhi Cai · Chongqing, CN

Key dates

Filing date	Dec 9, 2013
Grant date	Feb 13, 2018
Priority date	—
Expiry date	Dec 9, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/26
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided is staphylococcus protein A expressed by a mutational Staphylococcus aureus and its coding sequence, as well as a vector, host bacteria, composition or kit which contains the coding sequence of the mutational protein. Also provided is the use of the mutational protein and the composition thereof in the preparation of vaccines, therapeutic antibodies, diagnostic kits and the like, and for the prevention, treatment and detection of infections by Staphylococcus aureus. Also provided are methods for producing, fermenting and purifying the mutational protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.