Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids
US9890361B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 25, 2013 |
| Grant date | Feb 13, 2018 |
| Priority date | — |
| Expiry date | Sep 25, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of using viruses labeled with alkyne-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to increase the infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an alkyne-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The viruses labeled with alkyne-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.