Patent · US Active

Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression

US9890395B2 · kind B2 · utility

0Cited by

30References

11Claims

0Family size

Assignee

Sangamo Therapeutics, Inc. · US

Inventors

Trevor Collingwood · Chesterfield, US
Gregory J. Cost · Berkeley, US

Key dates

Filing date	Mar 24, 2016
Grant date	Feb 13, 2018
Priority date	—
Expiry date	Apr 21, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2800/80
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.