Biochemical markers for CVD risk assessment
US9891234B2 · kind B2 · utility
1Cited by
6References
7Claims
0Family size
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Key dates
| Filing date | May 4, 2012 |
| Grant date | Feb 13, 2018 |
| Priority date | — |
| Expiry date | Mar 1, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/323
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of bioassay for the quantification of peptide fragments comprising a neo-epitope formed by cleavage of mimecan, a protein of an atherosclerotic plaque, by a proteinase is provided. In the method a sample, such as urine or serum, is contacted with an antibody reactive with the neo-epitope and the level of binding of the antibody to peptide fragments in the sample is determined. The assay is predictive of risk of cardiovascular disease events.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.