Wet-electrospun biodegradable scaffold and uses therefor

US9901659B2 · kind B2 · utility

Assignee

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

• Yi Hong · Irving, US
• Nicholas J. Amoroso · Pittsburgh, US
• Kazuro Lee Fujimoto · Pittsburgh, US
• Ryotaro Hashizume · Pittsburgh, US
• William R. Wagner · Escondido, US

Key dates

• Filing date: May 27, 2011
• Grant date: Feb 27, 2018
• Expiry date: Jan 31, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/30
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A cell growth matrix is provided that comprises a biodegradable elastomeric polymer electrodeposited concurrently with a sprayed or electrosprayed liquid that is a physiological solution or which comprises a mammalian blood product such as serum, plasma or platelet rich plasma. The matrix is useful as a cell-growth matrix and for repair of a tissue in a mammal, for instance by implantation in a mammal at a site in need of repair, such as in an abdominal wall.