Patent · US Active

Benzamides and nicotinamides as Syk modulators

US9902688B2 · kind B2 · utility

0Cited by
6References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 10, 2016
Grant dateFeb 27, 2018
Priority date
Expiry dateMay 10, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.