Method for selecting stable proteins in non-standard physicochemical conditions
US9903873B2 · kind B2 · utility
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2References
17Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 4, 2006 |
| Grant date | Feb 27, 2018 |
| Priority date | — |
| Expiry date | Mar 26, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for selecting proteins stable in non-standard physicochemical conditions (temperature, pressure, pH, osmolarity, salinity, solvent, etc.) comprising the expression, in an extremophilic microorganism, of variants of the protein of interest in the form of a fusion protein with a reporter protein which is stable in extreme conditions and acts as a selection marker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.