Patent · US Active

Salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-hepatonic acid

US9908850B2 · kind B2 · utility

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Key dates

Filing dateMar 24, 2017
Grant dateMar 6, 2018
Priority date
Expiry dateMar 24, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/037
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease.

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