P2X3 and/or P2X2/3 compounds and methods
US9908879B2 · kind B2 · utility
4Cited by
23References
43Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 16, 2016 |
| Grant date | Mar 6, 2018 |
| Priority date | — |
| Expiry date | Jun 16, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R4 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.