Collagen matrix with locally controlled intrafibrillar and extrafibrillar mineral content and methods of producing
US9908929B2 · kind B2 · utility
1Cited by
3References
19Claims
0Family size
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Key dates
| Filing date | Jan 31, 2014 |
| Grant date | Mar 6, 2018 |
| Priority date | — |
| Expiry date | Aug 12, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A mineralized collagen matrix with an intrafibrillar and/or extrafibrillar gradient of mineralization for insertion replacement is disclosed. The intrafibrillar mineralization of the collagen matrix is formed by the addition of fetuin to the simulated body fluid. The gradient of intrafibrillar mineralization may stiffen the collagen matrix and simulate a natural insertion for improved cell infiltration and regeneration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.