Engineered subcellular compartments

US9909143B2 · kind B2 · utility

Assignee

• Regents of the University of Minnesota · US

Inventors

• Claudia Schmidt-Dannert · Windom, US
• Swati Choudhary Saurkar · St. Louis Park, US
• Maureen B. Quin · Saint Paul, US
• Mark Anton Held · Emeryville, US

Key dates

• Filing date: Oct 25, 2012
• Grant date: Mar 6, 2018
• Expiry date: Aug 25, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/582
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

This disclosure describes a cell that includes an engineered subcellular compartment that generally includes a proteinaceous shell that includes at least one bacterial microcompartment (BMC) polypeptide. In some embodiments, the engineered subcellular compartment can further include one or more targeted enzymes. We further describe methods of making and using such cells.