Time efficient ASL imaging with segmented multiband acquisition

US9911206B2 · kind B2 · utility

Assignees

• Siemens Healthcare Limited · DE
• NATIONAL INSTITUTES OF HEALTH (NIH) · US

Inventors

• Xiufeng Li · Beijing, CN
• Gregory J. Metzger · Lake Elmo, US
• Kamil Ugurbil · Minneapolis, US
• Dingxin Wang · Apple Valley, US

Key dates

• Filing date: Jan 13, 2016
• Grant date: Mar 6, 2018
• Expiry date: May 6, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/5616
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for generating a perfusion weighted image using ASL with segmented acquisitions includes dividing an anatomical area of interest into slices and performing an EPI acquisition process using an MRI system to acquire a control image dataset representative of the slices. An ASL preparation process is performed using the MRI system to magnetically label protons in arterial blood water upstream from the anatomical area of interest. Following a first time period, a multi-band EPI acquisition process is performed using the MRI system to acquire a first labeled image dataset representative of a first subset of the slices. Following a second time period, another multi-band EPI acquisition process is performed using the MRI system to acquire a second labeled image dataset representative of a second subset of the slices. A perfusion weighted image is generated by subtracting the first and second labeled image dataset from the control image dataset.