Patent · US Active

Combination therapy with an anti-hyaluronan agent and therapeutic agent

US9913822B2 · kind B2 · utility

22Cited by

115References

35Claims

0Family size

Assignee

HALOZYME, INC. · US

Inventors

Daniel C. Maneval · San Diego, US
H. Michael Shepard · San Diego, US
Curtis B. Thompson · San Diego, US

Key dates

Filing date	Mar 15, 2013
Grant date	Mar 13, 2018
Priority date	—
Expiry date	Mar 15, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y302/01035
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein is combination therapy containing an anti-hyaluronan agent, such as a polymer-conjugated hyaluronan-degrading enzyme, and a tumor-targeted taxane, and optionally a further chemotherapeutic agent such as a nucleoside analog. The combination therapy can be used in methods of treating cancers, and in particular solid tumor cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.