Vaccine vectors and methods of enhancing immune responses
US9913893B2 · kind B2 · utility
10Cited by
27References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 16, 2015 |
| Grant date | Mar 13, 2018 |
| Priority date | — |
| Expiry date | Feb 16, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.