Patent · US Active

Targeting and in vivo imaging of tumor-associated macrophages

US9913920B2 · kind B2 · utility

7Cited by

4References

9Claims

0Family size

Assignees

VIB VZW · BE
VRIJE UNIVERSITEIT BRUSSEL · BE

Inventors

Kiavash Movahedi · Frankfurt am Main, DE
Damya Laoui · Limal, BE
Steve Schoonooghe · Kessel-Lo, BE
Geert Raes · Sint-Genesius-Rode, BE
Patrick De Baetselier · Berchem, BE
Jo Van Ginderachter · Ninove, BE
Nick Devoogdt · Zemst, BE
Tony Lahoutte · Ganshoren, BE

Key dates

Filing date	Aug 6, 2015
Grant date	Mar 13, 2018
Priority date	—
Expiry date	May 28, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/35
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The disclosure relates to activities and characteristics of tumor-associated macrophages (TAMs). In particular, immunoglobulin single variable domains are provided against markers of TAMs, and methods using the same for in vivo imaging of tumor cells, as well as cancer diagnostics and therapeutics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.