Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells
US9914135B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 12, 2007 |
| Grant date | Mar 13, 2018 |
| Priority date | — |
| Expiry date | May 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6806
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and apparatus for the selection or processing of particles sensitive to the application of an external stimulus, in which is produced, by applying the external stimulus, the rupture/lysis of at least one selected particle or the fusion of first and second selected particles, by means of the organization of the particles using a first field of force by selectively energizing electrodes of an array of selectable electrodes having dimensions comparable to or smaller than those of the particles, applying to the electrodes a first configuration of stresses; and by applying to the electrodes a second configuration of stresses, so as to create a second field of force, located substantially close to at least one selected particle to be lysated or to a pair of first and second particles to be fused and such as to produce the application of a stimulus suited to produce their lysis or fusion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.