Patent · US Active

Naphthylamide compound, preparation method and use thereof

US9914707B2 · kind B2 · utility

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1References

20Claims

0Family size

Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Wenhu DUAN · Shanghai, CN
Jian Ding · Shanghai, CN
Yongcong Lv · Shanghai, CN
Hua Xie · Shanghai, CN

Key dates

Filing date	Feb 15, 2015
Grant date	Mar 13, 2018
Priority date	—
Expiry date	Feb 15, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D495/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a naphthylamide compound of the structure as represented by formula (I), medicinal salts, prodrugs and hydrates or solvates thereof, and also relates to a method of preparing the compounds, pharmaceutical compositions comprising the compounds and the uses thereof as protein tyrosine kinase inhibitors, particularly as VEGFR-2 inhibitors, in preparing drugs for preventing and treating diseases related to abnormal angiogenesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.