Methods of synthesizing a difluorolactam analog
US9914725B2 · kind B2 · utility
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7References
4Claims
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Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Mar 13, 2018 |
| Priority date | — |
| Expiry date | Mar 14, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/4006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to processes and intermediates for preparing compounds of formula (IA), wherein R1, R4, R5, R6, and L1 are as defined herein. Compounds of formula (IA) have been found useful as EP4 receptor agonists useful in the treatment of glaucoma, osteoporosis, neuropathic pain, and related disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.