Process for detection of DNA modifications and protein binding by a single molecule manipulation
US9915655B2 · kind B2 · utility
19Cited by
2References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 22, 2014 |
| Grant date | Mar 13, 2018 |
| Priority date | — |
| Expiry date | Jan 22, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method for determining whether a protein binds to a specific DNA sequence. This method is useful in particular for identifying modifications to the DNA sequence (e.g. methylations) via the binding of proteins that specifically recognize those modifications (e.g. antibodies), but also to identify the binding sequence on DNA of a variety of proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.